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High efficacy with five days schedule of oral fludarabine phosphate and cyclophosphamide in patients with previously untreated chronic lymphocytic leukaemia

✍ Scribed by Bruno Cazin; Marine Divine; Stéphane Leprêtre; Philippe Travade; Olivier Tournilhac; Alain Delmer; Jérôme Jaubert; Pierre Feugier; Brigitte Dreyfus; Béatrice Mahé; Bernard Grosbois; Frédéric Maloisel; Houchingue Eghbali; Charles Dumontet; Jacques Bénichou; Odile Guibon; Xavier Leleu; Michel Leporrier; Karim Maloum

Book ID
108675920
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
96 KB
Volume
143
Category
Article
ISSN
0007-1048

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Low-dose oral fludarabine plus cyclophos
Low-dose oral fludarabine plus cyclophosphamide in elderly patients with untreated and relapsed or refractory chronic lymphocytic Leukaemia
✍ Francesco Forconi; Alberto Fabbri; Mariapia Lenoci; Elisa Sozzi; Alessandro Gozz 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB

## Abstract Fludarabine plus cyclophosphamide (FC) at conventional doses is an effective treatment for chronic lymphocytic leukaemia (CLL). However, FC at standard doses may give hematological and non‐hematological toxicity, predominantly in the elderly. Intravenous or oral low‐dose FC regimens rem