The pharmacokinetic profile of high-dose mitomycin C was determined in blood plasma and urine of twelve patients with advanced malignancies in a program including autologous bone marrow transplantation. A total dose of 60 mg/m2 was given, either as a single 60-min infusion or divided into infusions
High-dose mitomycin C: activity in hepatocellular carcinoma
β Scribed by Arkom Cheirsilpa; Suthee Leelasethakul; Vorachart Auethaveekiat; Savitree Maoleekulpriroj; Nalinphan Kangsumrit; Pimpa Thanakaravit; Pisit Phanthumjida
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 370 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0344-5704
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## Abstract Seventyβone women with farβadvanced breast cancer resistant to standard chemotherapeutic agents were administered mitomycin C using an intermittent high dose schedule. One group consisted of 54 patients with measurable metastatic tumor; a second group consisted of 18 patients with nonme