## Abstract Autologous stem cell transplantation (ASCT) has enabled the use of highβdose alkylating agents either as a single agent or in combination with other cytotoxic agents and/or total body irradiation (TBI) for the treatment of multiple myeloma. Despite improved complete remission rates, rel
High-dose melphalan versus busulfan, cyclophosphamide, and etoposide as preparative regimens for autologous stem cell transplantation in patients with multiple myeloma
β Scribed by Don M. Benson Jr.; Patrick J. Elder; Thomas S. Lin; William Blum; Sam Penza; Belinda Avalos; Edward Copelan; Sherif S. Farag
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 192 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0145-2126
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## BACKGROUND Highβdose chemotherapy (HDC) with autologous stem cell transplantation (ASCT) as part of the initial treatment regimen improves progressionβfree survival (PFS) and overall survival (OS) for patients with multiple myeloma. The optimal preparative regimen for patients with
## Abstract ## BACKGROUND Today, intensive therapy that includes highβdose melphalan with autologous stem cell transplantation (ASCT) is considered standard therapy in younger patients with newly diagnosed myeloma. When the current trial was initiated, combined vincristine, doxorubicin, and dexame
## Abstract The recent development of reduced intensity conditioning and allotransplantation (RICT) has opened a new way to assure engraftment of donor cells while reducing early transplantβrelated mortality. We evaluated the combination of highβdose therapy and autologous peripheral blood stem cel