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High-dose melphalan is an effective salvage therapy in acute myeloid leukaemia patients with refractory relapse and relapse after autologous stem cell transplantation

✍ Scribed by Gesine Bug; Johannes Atta; Stefan A. Klein; Bernd Hertenstein; Lothar Bergmann; Simone Boehrer; Sabine Mousset; Dieter Hoelzer; Hans Martin

Publisher: Springer
Year: 2005
Tongue: English
Weight: 107 KB
Volume: 84
Category: Article
ISSN: 0939-5555
DOI: 10.1007/s00277-005-1075-8

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## Abstract ## BACKGROUND Today, intensive therapy that includes high‐dose melphalan with autologous stem cell transplantation (ASCT) is considered standard therapy in younger patients with newly diagnosed myeloma. When the current trial was initiated, combined vincristine, doxorubicin, and dexame