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High dose intravenous immunoglobulin treatment: Mechanisms of action

✍ Scribed by Peter Boros; Gabriel Gondolesi; Jonathan S. Bromberg

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
121 KB
Volume
11
Category
Article
ISSN
1527-6465

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✦ Synopsis

Intravenous immunoglobulin (IVIg) treatment was introduced as replacement therapy for patients with antibody deficiencies, but evidence suggests that a wide range of immune-mediated conditions could benefit from IVIg. The immunoglobulins are precipitated from human plasma by fractionation methods. In conclusion, the differences in basic fractionation methods and the addition of various modifications for purification, stabilization, and virus inactivation result in products significantly different from each other.

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