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High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma

✍ Scribed by Margarita Rojas; Beatrice Marie; Jean Michel Vignaud; Nadine Martinet; Joëlle Siat; Gilles Grosdidier; Ingolf Cascorbi; Kroum Alexandrov

Book ID
116332982
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
200 KB
Volume
207
Category
Article
ISSN
0304-3835

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## Abstract Bronchial epithelial cells are often exposed to airborne mutagens that have the potential to induce genetic changes involved in the development of lung cancer. Although lung tumors often display alterations in the expression of oncogenes and/or tumor suppressor genes, the role of specif