✦ LIBER ✦

High-dimensional solid-liquid phase diagrams involving compounds and polymorphs

✍ Scribed by Christianto Wibowo; Ketan D. Samant; Ka M. Ng

Publisher: American Institute of Chemical Engineers
Year: 2002
Tongue: English
Weight: 511 KB
Volume: 48
Category: Article
ISSN: 0001-1541
DOI: 10.1002/aic.690481009

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✦ Synopsis

Abstract

A systematic procedure for the generation and visualization of high‐dimensional isobaric phase diagrams for systems exhibiting compound formation and/or polymorphism is presented. Such phase diagrams are useful in synthesizing crystallization‐based separation processes for systems involving compounds and polymorphs, which are common in the production of pharmaceuticals. Polythermal as well as isothermal phase diagrams of multicomponent systems can be generated. Examples are provided to illustrate the procedure.

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