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High detection rate of aberrant methylation of p16 gene in the serum/plasma in patients with colorectal cancer

✍ Scribed by Fujiya, Kaori; Ashida, Toshifumi; Maemoto, Atsuo; Orii, Fumika; Fujiki, Takanori; Fujiya, Mikihiro; Einami, Katsuya; Watari, Jiroh; Saitoh, Yusuke; Shibata, Yoshimi; Obara, Takeshi; Kongo, Yutaka

Book ID
123233530
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
161 KB
Volume
118
Category
Article
ISSN
0016-5085

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## Abstract We previously proved that p16 promoter methylation present in the tumors of colorectal cancer patients can be detected in the serum of those same patients using methylation‐specific PCR (MSP). To seek the possibility that this technique could be applied to the monitoring of cancer recur