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High density of FOXP3-positive T cells infiltrating colorectal cancers with microsatellite instability

✍ Scribed by Benner, A; Michel, S; Tariverdian, M; Wentzensen, N; Hoefler, P; Pommerencke, T; Grabe, N; von Knebel Doeberitz, M; Kloor, M


Book ID
109999851
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
250 KB
Volume
99
Category
Article
ISSN
0007-0920

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High frequency of tumor-infiltrating FOX
✍ Daniel M. Frey; Raoul A. Droeser; Carsten T. Viehl; Inti Zlobec; Alessandro Lugl πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 331 KB πŸ‘ 1 views

Regulatory T cells (T reg ) inhibit the generation of host-versus-tumor immunity via suppression of tumor-specific effector T-cell responses and development of immune tolerance to neoplastic cells. The transcription factor forkhead box P3 (FOXP3) is an intracellular key molecule for T reg developmen