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High concentrations of low density lipoprotein decrease basement membrane-associated heparan sulfate proteoglycan in cultured endothelial cells

✍ Scribed by Bernhard Olgemöller; Erwin D. Schleicher; Susanne Schwaabe; Hans-Joachim Guretzki; Klaus D. Gerbitz


Book ID
115923570
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
314 KB
Volume
264
Category
Article
ISSN
0014-5793

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The effect of elevated glucose concentrations on the synthesis of basement membrane components was investigated in proliferating cultured porcine mesangial cells. Basement membrane associated heparan sulphate proteoglycan was determined by enzyme immunoassay with a specific antiserum recognizing the