High blood glucose level on hospital admission and poor neurological recovery after cardiac arrest
✍ Scribed by Dr. W. T. Longstreth Jr; Thomas S. Inui
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 472 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
✦ Synopsis
To evaluate the relationship between blood glucose and neurological recovery after cardiac arrest, we retrospectively reviewed our experience with 430 consecutive patients resuscitated after out-of-hospital cardiac arrest. All these patients had received variable amounts of intravenous 5% glucose solutions before admission. Awakening patients, those following commands or having comprehensible speech, were classified as to whether they suffered persistent neurological deficits. The mean blood glucose level on hospital admission was higher i n 154 patients w h o never awakened than in 276 who did awaken (mean, 341 versus 262 m g per 100 milliliters; p < 0.0005). Among the 276 who awakened, 90 patients with persistent neurological deficits had higher mean glucose levels on admission than did 186 without deficits (286 versus 25 1 m g per 100 milliliters; p < 0.02). These significant differences persisted after excluding all patients whose glucose levels were higher than 500 m g per 100 milliliters and after controlling for potentially confounding variables using multiple regression analysis.