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High- and low-affinity transport of L-leucine and L-DOPA by the hetero amino acid exchangers LAT1 and LAT2 in LLC-PK1 renal cells

✍ Scribed by Soares-da-Silva, P.

Book ID
126724900
Publisher
The American Physiological Society
Year
2004
Tongue
English
Weight
494 KB
Volume
287
Category
Article
ISSN
0363-6127

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System L, which is encoded by LAT1 and LAT2, is an amino acid transport system that transports neutral amino acids, including several essential amino acids in an Na+-independent manner. Due to its broad substrate selectivity, system L has been proposed to mediate the transport of amino-acid-related