High affinity uptake of taurine in neuronal and glial cells
β Scribed by Jacques Borg; Vladimir J. Balcar; Paul Mandel
- Book ID
- 118862793
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 142 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0006-8993
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π SIMILAR VOLUMES
The properties and cellular distribution of a high-affinity uptake mechanism for taurine have been investigated using separate populations of purified chick embryo neural retina neurons and glia. Purified neuronal monolayers, cultured in scrumfree medium. were incubated in radioactive taurine under
Taurine uptake in cultured cerebellar granule cells and astrocytes consisted of a saturable high-affinity component and nonsaturable diffusion. The transport constant (Km) was significantly lower and the maximal velocity (V) higher in granule cells than in astrocytes. The uptakes were strictly sodiu