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High-Affinity Receptors for Peptides of the Bombesin Family in Swiss 3T3 Cells

โœ Scribed by Ian Zachary and Enrique Rozengurt


Book ID
123632222
Publisher
National Academy of Sciences
Year
1985
Tongue
English
Weight
915 KB
Volume
82
Category
Article
ISSN
0027-8424

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๐Ÿ“œ SIMILAR VOLUMES


Characterization of a bombesin receptor
โœ James Sinnett-Smith; Ian Zachary; Enrique Rozengurt ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 949 KB

We have previously identified by chemical cross-linking a cell surface protein in Swiss 3T3 cells of apparent Mr 75,000-85,000, which may represent a major component of the receptor for peptides of the bombesin family in these cells [ 11. Because bombesin-like peptides may interact with other cell

Diacylglycerol treatment rapidly decreas
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The synthetic diacylglycerol 1-oleoyl-2-acetyl glycerol (OAG) and phorbol esters activate protein kinase C in intact cells. We report here that OAG inhibits the binding of 125I-labelled epidermal growth factor (125I-EGF) to Swiss 3T3 cells. The inhibition was detected as early as 1 min after treatme