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High-affinity choline uptake carrier in Alzheimer's disease: implications for the cholinergic hypothesis of dementia

✍ Scribed by Julio Pascual; Aurora Fontán; Juan J. Zarranz; José Berciano; Jesús Flórez; Angel Pazos


Book ID
115801763
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
501 KB
Volume
552
Category
Article
ISSN
0006-8993

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Cognitive deficits in olivopontocerebell
✍ Dr. Stephen J. Kish; Munir El-Awar; Lawrence Schut; Larry Leach; Marchlene Oscar 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 689 KB

A cerebral cortical cholinergic reduction in dominantly inherited olivopontocerebellar atrophy (OPCA) was recently described. Although the magnitude of the cholinergic reduction was similar to that observed in Alzheimer's disease (AD), none of the OPCA patients was reported to have been demented. We