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HIF and reactive oxygen species regulate oxidative phosphorylation in cancer

✍ Scribed by Hervouet, E.; Cizkova, A.; Demont, J.; Vojtiskova, A.; Pecina, P.; Franssen-van Hal, N. L.W.; Keijer, J.; Simonnet, H.; Ivanek, R.; Kmoch, S.; Godinot, C.; Houstek, J.

Book ID: 121833188
Publisher: Oxford University Press
Year: 2008
Tongue: English
Weight: 585 KB
Volume: 29
Category: Article
ISSN: 0143-3334
DOI: 10.1093/carcin/bgn125

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## Abstract Stem cells are defined by their ability to self‐renew and their multi‐potent differentiation capacity. As such, stem cells maintain tissue homeostasis throughout the life of a multicellular organism. Aerobic metabolism, while enabling efficient energy production, also generates reactive