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HIF-1alpha is a novel target of the SWI/SNF chromatin remodelling complex

✍ Scribed by S. Rocha; N.S. Kenneth; P. van Uden; S. Mudie


Book ID
119598752
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
6
Category
Article
ISSN
1359-6349

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✍ Diana Vradii; Stefan Wagner; Diem N. Doan; Jeffrey A. Nickerson; Martin Montecin 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 406 KB

## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or