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Hierarchical unfolding of the α-lactalbumin molten globule: presence of a compact intermediate without a unique tertiary fold

✍ Scribed by Suroopa Chakraborty; Zheng-yu Peng


Book ID
115630151
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
173 KB
Volume
298
Category
Article
ISSN
0022-2836

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✍ Klaus Gast; Dietrich Zirwer; Marlies MÜller-Frohne; Gregor Damaschun 📂 Article 📅 1998 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 851 KB

## Abstract During folding of globular proteins, the molten globule state was observed as an equilibrium intermediate under mildly denaturing conditions as well as a transient intermediate in kinetic refolding experiments. While the high compactness of the equilibrium intermediate ofα‐lactalbumin h