Hiccups with high dose dexamethasone administration : A case report

✍ Scribed by Robert J. Cersosimo; Mary T. Brophy

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 52 KB
• Volume: 82
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19980115)82:2<415::aid-cncr23>3.0.co;2-0

✦ Synopsis

METHODS. The strong temporal relation between dexamethasone administration

and the occurrence of hiccups indicated that dexamethasone was the cause of the 2 Department of Hematology and Medical Onpatient's hiccups. Because he was responding to dexamethasone, the decision was cology, VA Medical Center, Boston, Massachumade to continue therapy and to relieve his hiccups with metoclopramide. setts.

RESULTS.

Low dose oral metoclopramide allowed the patient to continue therapy without a recurrence of the hiccups.

CONCLUSIONS. Dexamethasone administration can result in intractable hiccups

that persist for the duration of therapy. Low dose oral metoclopramide may prevent hiccups in patients in whom the discontinuation of dexamethasone therapy is not appropriate.