The role of GB virus-C/hepatitis G virus (GBV-C/ HGV), a recently identified member of the Flaviviridae family, in children with liver disease is not well understood. The aims of this study were to evaluate the prevalence of GBV-C/HGV and to clarify its pathogenic role in young patients with chronic
HGV/GBV-C infection in patients with acute hepatitis of different etiology and in patients with chronic hepatitis C
β Scribed by Paolo Fabris; Domenico Infantolino; Maria Raffaella Biasin; Paolo Benedetti; Giulia Tositti; Costanza Bettini; Giuditta Marchelle; Fausto de Lalla
- Publisher
- Springer Japan
- Year
- 1998
- Tongue
- English
- Weight
- 114 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0944-1174
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A novel virus (GBV-C/HGV) may be associated with some liver diseases including fulminant hepatitis and acute and chronic hepatitis. On the other hand, many investigations showed that this infection does not contribute to liver disease. GBV-C/HGV has been found to occur in association with infection
Sera from patients with chronic hepatitis C were examined for the presence of GBV-C/HGV RNA by RT-PCR. The amplified products, derived from the 5' non-coding, NS3, and NS5a regions, were detected in 19 (19%) of the 100 HCV RNA-positive samples. Analysis of GBV-C/HGV prevalence rates revealed that du
We compared characteristics of patients with GB virus C/hepatitis G virus (GBV-C/HGV) RNA to those of patients with GBV-C/HGV E2-antibody. GBV-C/HGV RNA and GBV-C/HGV antibody were assayed in 83 persons with hemophilia using a reverse transcription-polymerase chain reaction and an enzyme-linked immu