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HGF promotes survival and growth of maturing sympathetic neurons by PI-3 kinase- and MAP kinase-dependent mechanisms

โœ Scribed by Jane Thompson; Xavier Dolcet; Mark Hilton; Mary Tolcos; Alun M. Davies


Book ID
116735228
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
536 KB
Volume
27
Category
Article
ISSN
1044-7431

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Insulin receptor-related receptor (IRR) expression is tightly coupled to the nerve growth factor (NGF) receptor, TrkA, throughout development. Expression of both receptors is primarily localized to neural crest derived sensory and sympathetic neurons. In contrast to TrkA, however, the physiological