Antisense glutaminase inhibition modifie
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Ana C. Donadio; Carolina Lobo; Marta Tosina; Vanessa de la Rosa; Mercedes MartΓn
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Article
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2008
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John Wiley and Sons
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English
β 263 KB
## Abstract Glutamine behaves as a key nutrient for tumors and rapidly dividing cells. Glutaminase is the main glutamineβutilizing enzyme in these cells, and its activity correlates with glutamine consumption and growth rate. We have carried out the antisense Lβtype glutaminase inhibition in human