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Hexosamine flux, the O-GlcNAc modification, and the development of insulin resistance in adipocytes

✍ Scribed by Chin Fen Teo; Edith E. Wollaston-Hayden; Lance Wells


Book ID
116734665
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
780 KB
Volume
318
Category
Article
ISSN
0303-7207

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## Abstract Glutamine behaves as a key nutrient for tumors and rapidly dividing cells. Glutaminase is the main glutamine‐utilizing enzyme in these cells, and its activity correlates with glutamine consumption and growth rate. We have carried out the antisense L‐type glutaminase inhibition in human