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Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons

✍ Scribed by Ji Yeon Jang; Ha Neui Kim; Yu Ri Kim; Young Whan Choi; Yung Hyun Choi; Jun Hyuk Lee; Hwa Kyoung Shin; Byung Tae Choi


Book ID
119295589
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
939 KB
Volume
145
Category
Article
ISSN
0378-8741

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## Abstract Glutamate toxicity causes neuronal death in neurodegenerative diseases; hence, there is a need for therapeutic agents rendering functional neuroprotection. We tested the effects of 17β‐estradiol (estrogen) in rat primary cortical neurons after glutamate exposure. Wright staining and Apo