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Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension

✍ Scribed by Cummings, David E; Schwartz, Michael W.


Book ID
109828891
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
504 KB
Volume
26
Category
Article
ISSN
1061-4036

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## Communicated by Maria Rita Passos-Bueno Pulmonary arterial hypertension (PAH) is clinically characterized by a sustained elevation in mean pulmonary artery pressure leading to significant morbidity and mortality. The disorder is typically sporadic, and in such cases the term idiopathic PAH (IPAH