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Heterozygous female carriers of the marker-X-chromosome: IQ estimation and replication status of fra(X)(q)

✍ Scribed by J. Paul; Ursula Froster-Iskenius; W. Móje; E. Schwinger


Publisher
Springer
Year
1984
Tongue
English
Weight
446 KB
Volume
66
Category
Article
ISSN
0340-6717

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✍ Wilhelm, Dorothea ;Froster-Iskenius, Ursula ;Paul, Jürgen ;Schwinger, Eberhard 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 2 views

Female heterozygotes of the fra(X) form of mental retardation show variable degrees of mental impairment and phenotype expression of the disorder. This might be an effect of inactivation of the X-chromosome which carries the fra(X)(q). Prior replication studies in heterozygous carriers gave contradi