Heterozygous ATM mutations do not contribute to early onset of breast cancer
โ Scribed by FitzGerald, Michael G.; Bean, James M.; Hegde, Sanjay R.; Unsal, Hilal; MacDonald, Deborah J.; Harkin, D. Paul; Finkelstein, Dianne M.; Isselbacher, Kurt J.; Haber, Daniel A.
- Book ID
- 109915474
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 404 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1061-4036
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Epidemiological studies have shown an increased risk of breast cancer in obligate ataxia telangiectasia (A-T) heterozygotes. We analyzed 100 samples from young breast cancer patients for mutations in ataxia-telangiectasia mutated (ATM), the gene responsible for the autosomal recessive condition, A-T