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Heteronuclear Edited Gradient Selected 1D and 2D NOE Spectra: Determination of the NOE Effect between Chemically Equivalent Protons

✍ Scribed by Ronald Wagner; Stefan Berger


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
268 KB
Volume
35
Category
Article
ISSN
0749-1581

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✦ Synopsis


With gradient selected HSQC-NOESY spectra it is possible to detect the NOE e †ect between protons which have the same chemical shift either due to symmetry or due to accidental overlap. The discrimination of the equivalent sites is achieved by allowing one site to couple with 13C in natural abundance. The suppression of unwanted signals is performed with pulse Ðeld gradient selection. Both 2D and selective 1D methods are shown.