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Heterolytic fragmentation of pregnane-16,20-diol derivatives to androst-16-enes

✍ Scribed by Matsui, Michio.; Fukushima, David K.


Book ID
115535440
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
598 KB
Volume
35
Category
Article
ISSN
0022-3263

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A Ready Conversion of a Pregnane-20-carb
✍ Biancini, Bruno ;Caciagli, Valerio ;Centini, Felice ;Eletti-Bianchi, Giancarlo ; 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 412 KB

## Abstract Reaction of (20__S__)‐5α‐chloro‐3β‐hydroxypregnane‐20‐carboxaldehyde (**9**, prepared in two steps from stigmasterol) with oxygen and potassium __tert__‐butoxide, followed by trimethyl phosphite treatment, afforded 5α‐chloro‐3β,17α‐dihydroxypregnan‐20‐one (**6**) and 3β,17α‐dihydroxypre