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Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck

✍ Scribed by Bestvater, Thorsten ;Louis, Petra ;Galinski, Erwin A

Book ID
119909894
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
610 KB
Volume
4
Category
Article
ISSN
1746-1448

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## Abstract 6‐Deoxyerythronolide B (6dEB) is the macrocyclic aglycone precursor of the antibiotic natural product erythromycin. Heterologous production of 6dEB in __Escherichia coli__ was accomplished, in part, by designed over‐expression of a native __prpE__ gene (encoding a propionyl‐CoA syntheta