Heterogeneous immunoreactivity of glial cells in the mesencephalon of a lizard: A double labeling immunohistochemical study
✍ Scribed by Maximina Monzón-Mayor; Carmen Yanes; Jean De Barry; Carmen Capdevilla-Carbonell; Jaime Renau-Piqueras; Georges Tholey; Giorgio Gombos
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 697 KB
- Volume
- 235
- Category
- Article
- ISSN
- 0362-2525
No coin nor oath required. For personal study only.
✦ Synopsis
Astrocytes and radial glia coexist in the adult mesencephalon of the lizard Gallotia galloti. Radial glia and star-shaped astrocytes express glial fibrillary acidic protein (GFAP) and glutamine synthetase (GS). The same cell markers are also expressed by round or pear-shaped cells that are therefore astrocytes with unusual morphology.
Other round or pear-shaped cells, also scattered in the tegmentum and the tectum, display only GS. Electron microscopy reveals that these cells may be oligodendrocytes. In this lizard, the GS is expressed in some oligodendrocytes while this does not occur in the central nervous system of mammals in situ. These results confirm that the cellular specificity of GS is different in various species and suggest that ependymal cells are also immunoreactive for GS but they do not contain GFAP.
📜 SIMILAR VOLUMES
Immunoperoxidase methods for the demonstration of three glial antigens, vimentin, glial fibrillary acidic protein, and S-100 protein, were applied to routine-fixed paraffin sections of rat pineal gland. A pre-embedding electron microscope immunoperoxidase method was also used to study the ultrastruc