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Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues

✍ Scribed by Mi-Yeon Kim; Simona Rossi; David Withers; Fiona McConnell; Kai-Michael Toellner; Fabrina Gaspal; Eric Jenkinson; Graham Anderson; Peter J. L. Lane

Book ID: 108782238
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 788 KB
Volume: 124
Category: Article
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.2007.02750.x

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Cover Picture: The cover image features

Cover Picture: The cover image features a frozen section from an embryonic day 16 mouse spleen stained by immunofluorescence to demonstrate the presence and location of lymphoid tissue inducer (LTi) cells. Withers et al. (pp. 3240–3245) show that these cells form the focus of lymphocyte accumulation in the developing mouse spleen. Red staining for CD45 marks haemopoietic cells, green shows IL-7Rα expression, and CD4 expression is in blue. LTi cells that express all markers (in white) cluster around blood vessels in the embryonic spleen where signalling to stromal cells initiates lymphocyte recruitment. – Eur. J. Immunol. 11/2007

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