In patients with cancer, antibody-dependent cellular cytotoxicity (ADCC) may be used as a laboratory test or for enhancing immunotherapy with murine monoclonal or chimeric mouse/ human anti-tumor antibodies (mMAbs or cMAbs, respectively). We have established an ADCC assay with lgG, cMAb SF-25, using
β¦ LIBER β¦
Heterogeneity of human natural killer recognition demonstrated by cloned effector cells and differential blocking of cytotoxicity with monoclonal antibodies
β Scribed by Graham Pawelec; Walter Newman; Udo Schwulera; Peter Wernet
- Book ID
- 113133182
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 702 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-8749
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## Abstract Cells from two melanoma cell lines, Me43 and GLLβ19, were cloned in methylcellulose cultures and 20 randomly selected colonies from each line were picked up by microβmanipulation, expanded in liquid cultures, and considered as clones of the original cell lines. The antigenic cell surfac
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