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Heterogeneity in senile dementia of the Alzheimer type: Individual differences, progressive deterioration or clinical sub-types?

✍ Scribed by Ritchie, Karen; Touchon, Jacques


Book ID
123560763
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
979 KB
Volume
45
Category
Article
ISSN
0895-4356

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The muscarinic agonist RS 86 was administered to patients with Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT) in a series of controlled clinical trials. Daily doses were up to 3.0 mg orally for a maximum duration of 18 weeks. RS 86 produced typical peripheral cholinergic e