Heterogeneity in longitudinal evolution of ring-enhancing multiple sclerosis lesions

✍ Scribed by Peiqing Qian; Diego Cadavid; Leo J. Wolansky; Stuart D. Cook; Robert T. Naismith

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 103 KB
• Volume: 70
• Category: Article
• ISSN: 0364-5134
• DOI: 10.1002/ana.22622

✦ Synopsis

States due to recrystallization/ formulation issues and still remains unavailable here. Although tolcapone appears to provide a longer duration of action than entacapone, in a recent study in which patients were switched from entacapone to tolcapone, dyskinesias were reported relatively frequently, in 29% of entacapone versus 31% of tolcapone patients. 3 Although these agents may relieve motor symptoms, neither provides CDS. The challenge of providing true CDS using noninvasive methods remains largely unmet; however, some strategies may indeed move us closer to that goal.