✦ LIBER ✦

Heterogeneity and statistical significance in meta-analysis: an empirical study of 125 meta-analyses

✍ Scribed by Eric A. Engels; Christopher H. Schmid; Norma Terrin; Ingram Olkin; Joseph Lau

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 233 KB
Volume: 19
Category: Article
ISSN: 0277-6715
DOI: 10.1002/1097-0258(20000715)19:13<1707::aid-sim491>3.0.co;2-p

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Meta-analysis of DRD3 gene and schizophr

Meta-analysis of DRD3 gene and schizophrenia: Ethnic heterogeneity and significant association in caucasians

✍ Dubertret, Caroline; Gorwood, Philip; Ades, Jean; Feingold, Josue; Schwartz, Jea 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 33 KB 👁 2 views

The involvement of dopamine in the etiology of schizophrenia is suggested by a number of neurobiological and pharmacological data, the dopamine D3 receptor (DRD3) being selectively expressed in brain regions which may be specifically involved in the risk for schizophrenia. The gene coding for DRD3 h

Variation in baseline risk as an explana

Variation in baseline risk as an explanation of heterogeneity in meta-analysis

✍ S.D. Walter 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 1 views

A relationship of baseline risk to treatment effect size has been suggested as a possible explanation of between-study heterogeneity in meta-analyses. To address this question, we develop regression models to examine the relationship between the logits (or other response measure) in the intervention

Variation in baseline risk as an explana

Variation in baseline risk as an explanation of heterogeneity in meta-analysis by S. D. Walter, Statistics in Medicine, 16, 2883-2900 (1997)

✍ R. M. D. Bernsen; M. J. A. Tasche; N. J. D. Nagelkerke 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB 👁 1 views

With many research groups in the world studying the same or similar types of intervention, there is an opportunity and a need to collate and synthesize all available evidence on the value of specific interventions. Thus, meta-analysis, the statistical science of doing this, is becoming increasingly

An empirical study of the effect of the

An empirical study of the effect of the control rate as a predictor of treatment efficacy in meta-analysis of clinical trials

✍ Christopher H. Schmid; Joseph Lau; Martin W. McIntosh; Joseph C. Cappelleri 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB 👁 2 views

Analysis of the monoamine oxidase A (MAO

Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter

✍ Furlong, Robert A.; Ho, Luk; Rubinsztein, Judy S.; Walsh, Cathy; Paykel, Eugene 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB 👁 2 views

Monoamine oxidases catalyse the oxidative degradation of biogenic amines including neurotransmitters such as noradrenaline, dopamine, and 5-hydroxytryptamine (5-HT). Three groups have reported positive associations of the monoamine oxidase A (MAOA) gene with bipolar affective disorder although other

Investigating underlying risk as a sourc

Investigating underlying risk as a source of heterogeneity in meta-analysis by S. G. Thompson, T. C. Smith and S. J. Sharp, Statistics in Medicine, 16, 2741–2758 (1997)

✍ Hans van Houwelingen; Stephen Senn 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB 👁 1 views

In a recent issue of Statistics in Medicine, Thompson, Smith and Sharp (TSS) discussed an issue that we have both separately considered in this journal before. They consider approaches through meta-analysis to examining the relationship of the efficacy of treatment to the 'underlying risk', where th