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Heterogeneity and recurrence risk for congenital hydrocephalus (Ventriculomegaly): A prospective study

✍ Scribed by Váradi, Valéria ;Tóth, Zoltán ;Török, Olga ;Papp, Zoltán ;Optiz, John M. ;Reynolds, James F.

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
349 KB
Volume
29
Category
Article
ISSN
0148-7299

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✦ Synopsis

We report on 261 prospectively ascertained pregnancies studied to determine the recurrence risk of congenital hydrocephalus. Our results suggest that couples who have had one previous child with hydrocephalus have a recurrence risk of 4%. Such couples should be offered prenatal diagnosis in the second trimester of all subsequent pregnancies. It is suggested that, apart from the X-linked recessive cases, ventriculomegaly is mostly multifactorially determined.

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