Heterogeneity and Polymorphism of Human-Liver Alcohol Dehydrogenase
β Scribed by Toni M. Schenker; Leslie J. Teeple; Jean-Pierre von Wartburg
- Book ID
- 115112967
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 865 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1432-1327
No coin nor oath required. For personal study only.
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New molecular forms of human liver alcohol dehydrogenase (ADH), collectively designed ADH Indianapolis (ADHInd), were recently discovered in 29% of liver specimens from Black Americans [Bosron, W. F., Li, T.-K., and Vallee, B. L. (1981). Proc. Natl. Acad.Sci. USA 77:5784]. Three different ADHInd phe
Human liver alcohol dehydrogenase isozyme patterns were studied using prolonged high voltage starch-gel electrophoresis and gel-slab isoelectric focusing. Homo- and heterodimers of ADH2 locus were easily distinguished from each other. The gene frequencies of ADH2 2 and ADH2 3 in 46 random liver samp