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Heterogeneity and Common Features of Defective Hepatitis B Virus Genomes Derived from Spliced Pregenomic RNA

✍ Scribed by Stephan Günther; Gunhild Sommer; Alicja Iwanska; Hans Will

Book ID: 112271797
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 647 KB
Volume: 238
Category: Article
ISSN: 0042-6822
DOI: 10.1006/viro.1997.8863

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## Abstract In hepatitis B virus (HBV) replication cycle, pregenomic RNA undergoes splicing and the reverse transcribed defective genomes can be packaged and released. Various types of spliced defective HBV genomes have been isolated from the sera and liver tissues of viral hepatitis B patients. To