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Heterodetic bicyclic decapeptide cyclo (Glu1 -Leu2 -Pro3-Gly4-Ser5-Ile6-Pro7-Ala8) cyclo-(1γ-5β) Phe9-Gly10

✍ Scribed by BARBATO, GAETANO ;D'AURIA, GABRIELLA ;PAOLILLO, LIVIO ;ZANOTTI, GIANCARLO

Book ID
115099184
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
797 KB
Volume
37
Category
Article
ISSN
0367-8377

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📜 SIMILAR VOLUMES

Bicyclic peptides: Solution conformation
Bicyclic peptides: Solution conformation and Ca2+ binding of the heterodetic bicyclic decapeptide cyclo(Glu1-Leu2-Pro3-Gly4-Ser5-Ile6-Pro7-Ala8)-cyclo(1γ → 5β) Phe9-Gly10
✍ Giancarlo Zanotti; Francesco Pinnen; Gino Lucente; Livio Paolillo; Gabriella D'A 📂 Article 📅 1989 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 750 KB

The conformational behavior of a heterodetic bicyclic decapeptide (BCPLT) in the absence and in the presence of calcium ions has been studied by means of mono and two-dimensional nmr techniques. Free BCPLT possessee a quite compact structure stabilized by intramolecular bonds and turns. In the struc

Nmr and computer-aided studies of the th
Nmr and computer-aided studies of the three interchanging stereoisomers of the cyclic hexapeptide cyclo[-Pro1-Gly2-Glu3(OBzl)-Pro4-Phe5-Leu6-]: Unexpected observation of a cis isomer of a secondary amide peptide bond in the presence of two trans proline peptide bonds
✍ Ian Mc Ewen 📂 Article 📅 1993 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 692 KB

The cyclic hexapeptide cycle[ -Pro'-Gly2-Glu3 (OBzl) -Pro4-Phe5-Leu6-] ( 1 ; OBzl: benzyl ester) was modeled and synthesized to be used as a chiral site for the separation of enantiomers. Total correlation spectroscopy and nuclear Ovehauser effect spectroscopy spectra of the peptide in CDCIB showed