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Heterocyclization of 3-aminocamphor and 3-aminoisoborneol derivatives with cyclicβ-diketones and formaldehyde. Synthesis of optically active 1,2,3,4-tetrahydroquinoline derivatives with terpene substituents

✍ Scribed by A. P. Kadutskii,N. G. Kozlov,L. L. Frolova…


Book ID
118298294
Publisher
Springer
Year
2012
Tongue
English
Weight
117 KB
Volume
48
Category
Article
ISSN
0009-3130

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## A facile, one-step synthesis of 2-amino-5-oxo-5,6,7,8tetrahydro-4H-benzopyran derivatives 4a-e via cycloaddition reactions of acrylonitrile derivatives la-e with 1,3-cyclohexandione 2 is described. On the other hand, the reactions of 2 with the thioamides If-h afforded 5-0~0-5,6,7,8-tetrahydroq