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Heterocyclically bridged tricyclic β-lactames: A simple synthesis of 1,2,2a,8a-tetrahydro-3-oxa-1-aza-cyclobuta[b]naphthalen-2-ones

✍ Scribed by A. Takó; K. -H. Ongania; K. Wurst


Publisher
Springer Vienna
Year
1997
Tongue
English
Weight
502 KB
Volume
128
Category
Article
ISSN
0026-9247

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ChemInform Abstract: Heterocyclically Br
✍ A. TAKO; K.-H. ONGANIA; K. WURST 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

Heterocyclically Bridged Tricyclic β-Lactames: A Simple Synthesis of 1,2,2a,8a-Tetrahydro-3-oxa-1-aza-cyclobuta[b]naphthalen-2-ones. -The novel title heterocycles such as (VI) and (VII) are obtained via 6-exo-trig radical cyclization. The structure of compound (VIIb) is confirmed by X-ray analysis.

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✍ Navnath Dnyanoba Yadav; Masayuki Yamashita; Masaki Nagahama; Tomoki Inaba; Takes 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 128 KB

When 1-substituted 2a-aroyl-1,2,2a,8b-tetrahydro-3H-benzo[b]cyclobuta [d]pyran-3-ones (1) were treated with dimethylsulfoxonium methylide, 1-endo isomers (endo-1) gave 1-substituted 3-aroyl-1,2,4a,9b-tetrahydrodibenzofuran-4-ols (2) exclusively as expected. On the other hand, 1-exo isomers (exo-1) u