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Heterocyclic variants of the 1,5-benzodiazepine system. VIII. Reaction of 4(7)-aminobenzimidazole with ethyl 2-alkylmalonates

✍ Scribed by Roberto Martínez; Lucia Valle; Marcos Gonzalez; Claudia Romano


Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
198 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Reaction of 4(7)‐aminobenzimidazole with ethyl 2‐alkylmalonates gave the novel 4,5,6,7‐tetrahydro‐5‐alkyl‐imidazo[1,5,4‐ef][1,5]benzodiazepine‐4,6‐diones, and the 2‐alkyl‐4(7)‐(2′‐ethoxycarbonyl)acetamido‐benzimidazoles. The structure of all the products was corroborated by ir, mass spectrometry and ^1^H‐nmr.


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