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Heterocyclic synthesis with 3-cyano-2(1H)pyridinethione: Synthesis of 3-oxo-2,3-dihydroisothiazolo[5,4-b]pyridine and related compounds

✍ Scribed by A. Deeb; A. Essawy; A. M. El-Gendy; A. Shaban


Publisher
Springer Vienna
Year
1990
Tongue
English
Weight
357 KB
Volume
121
Category
Article
ISSN
0026-9247

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Synthesis of substituted 3-amino-4-cyano
✍ Reinhard TroschΓΌtz; Annin Hoffmann πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 830 KB

## Abstract The preparation of 3‐amino‐ and 3‐dialkylamino‐4‐cyanoazepino[3,4‐fc]indoles bearing substituents on the aromatic nucleus and N^10^ is outlined. Starting from suitable substituted ethyl 3‐formylindole‐2‐carboxy‐latcs 2, condensation with malononitrile (3) and subsequent sodium borohydri