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Heterocyclic Studies. III. A Ring Closure Reaction of Diazoacetylpyrazolines

โœ Scribed by Moore, James A.; Medeiros, Robert W.


Book ID
127156492
Publisher
American Chemical Society
Year
1959
Tongue
English
Weight
371 KB
Volume
81
Category
Article
ISSN
0002-7863

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A general method for the synthesis of isocoumarine derivatives has been developed. Bis(5-R-2furyl)methylbenzoic acids (R = methyl, ethyl) underwent recyclization and subsequent cyclization into tetracyclic isochromene-1-one derivatives under treatment with hydrogen chloride in methanol. It has been