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Heterocellular Hereditary Persistence of Fetal Haemoglobin (Heterocellular HPFH) and its Interaction with β Thalassaemia

✍ Scribed by W. G. Wood; D. J. Weatherall; J. B. Clegg; T. J. Hamblin; J. H. Edwards; A. M. Barlow

Book ID: 114708642
Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 817 KB
Volume: 36
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.1977.tb00986.x

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Some types of nondeletional heterocellular hereditary persistence of fetal hemoglobin (HPFH) appear to be caused by mutations in the beta globin gene cluster near the gamma globin genes, while in other cases the condition is associated with a gene or genes outside the beta globin gene complex. We ha