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Heteroannulation through copper catalysis: a novel cyclisation leading to an unusual formation of 2-aroylquinoxalines

✍ Scribed by Rupa Mukhopadhyay; Nitya G Kundu

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
70 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

N- [(3%-Aryl)prop-2%-ynyl]-N,N%-1,2-phenylene di-p-tosylamides, 15-22, underwent an unusual ring closure with potassium carbonate (2 equiv.) and copper(I) iodide (10 mol%) in DMF at 100Β°C for 24 h to yield 2-aroylquinoxalines (23-30) instead of the expected 2-alkylidene-1,4-di-tosyl-1,2,3,4-tetrahydroquinoxalines (31).

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