Heteroadamantanes and their derivatives. 7. Synthesis and mass-spectrometric study of functional derivatives of 5-mono- and 5,7-disubstituted 1,3-diazaadamantanes
β Scribed by A. I. Kuznetsov; E. B. Basargin; M. Kh. Ba; A. S. Moskovkin; I. V. Miroshnichenko; M. Ya. Botnikov
- Publisher
- Springer US
- Year
- 1989
- Tongue
- English
- Weight
- 542 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0009-3122
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## Abstract A series of 2,5βdisubstituted 1,3,5βdithiazine derivatives were synthesized as potential analogues of the potent dopamine uptake inhibitor GBR 12909. The lipophilic character of the 1,3,5βdithiazine derivatives were experimentally (log __P__) and computationally (clog __P__) determined.
10 12 4 10 12 4 Ionization potentials, HOMO and LUMO energies, energy gaps, heats of formation, atomization energies, and vibration frequencies were calculated. These calculations w 3,7 x indicate that these molecules are stable and have T symmetry. Tricyclo 3,3,1,1 decd Ε½ . silane and its halogen