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Hershberger assay: Testing of coded chemicals and supplementary molecular and biochemical investigations

✍ Scribed by A. Freyberger; H. Ellinger-Ziegelbauer; A. Brockes; F. Krötlinger


Book ID
119378713
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
103 KB
Volume
164
Category
Article
ISSN
0378-4274

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## Abstract As a participating laboratory for the OECD Hershberger validation program, we conducted a phase 3 trial to test the reliability of the Hershberger assay using coded substances. Male Sprague–Dawley rats were castrated at 6 weeks of age and allowed to recover for 8 days. All the coded sub