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Herpesvirus ateles: Transformation in vitro of marmoset splenic lymphocytes

✍ Scribed by Lawrence Falk; John Wright; Lauren Wolfe; Friedrich Deinhardt

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
586 KB
Volume
14
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Four lymphoblastoid cell cultures were established by transformation of marmoset splenic lymphocytes in vitro with Herpesvirus ateles (HVA). The association of HVA with each cell line was demonstrated by the recovery of HVA from the lymphoblastoid cells or from the culture fluids and by the demonstration of HVA antigens in a small percentage of cells of each lymphoblastoid culture. Intranuclear inclusion bodies were observed in three cultures examined but herpesvirus virions were observed in only one of three cell lines. The four cell cultures had properties of T‐lymphocytes.

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