Herpes simplex virus type 2 infection of neonatal mice
β Scribed by D. A. Baker; S. A. Plotkin
- Publisher
- Springer-Verlag
- Year
- 1978
- Tongue
- English
- Weight
- 426 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0300-8126
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A disseminated herpes virus type 1 infection in a baby was acquired from the father, who had herpes labialis. This was shown by virus strain typing using restriction endonuclease DNA analysis. Labial herpes, a common infection in adults, must be recognised as a potential threat to newborn babies.
## Abstract Factors that influence the outcome of genital herpes simplex virus (HSV) infection were explored in a guinea pig model. The viral inoculum required to establish infection in 50% of animals (ID~50~) was similar for inbred (strain 2) and outβbred (Hartley) guinea pigs. However, the viral